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Event counts by trial and corticosteroid subgroup from the WHO REACT prospective meta-analysis of IL-6 antagonists in patients hospitalized for COVID-19. Some trials report only one corticosteroid subgroup (n = 0 patients in the other subgroup); drop those empty rows before escalc() and let ifrac() / cams() complete the missing cells. See vignette("worked-examples").

Usage

data(il6)

Format

A data frame with 30 rows and 7 variables:

study

Study identifier.

subgroup

Corticosteroid subgroup (yes / no).

n

Total patients (treat.total + cont.total).

treat.events

Events in the treatment arm.

treat.total

Total subjects in the treatment arm.

cont.events

Events in the control arm.

cont.total

Total subjects in the control arm.

Source

WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, Sterne JAC, Murthy S, et al. (2021). Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19: a meta-analysis. JAMA, 326(6), 499–518. https://doi.org/10.1001/jama.2021.11330

https://pubmed.ncbi.nlm.nih.gov/34228774/